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May 15, 2022

Sodium/potassium ratio change is associated with the blood pressure levels changes: odds of society method for sodium/potassium ratio loss in fitness checkup

Sodium/potassium ratio change is associated with the blood pressure levels changes: odds of society method for sodium/potassium ratio loss in fitness checkup

Recently, the sodium (Na)/potassium (K) ratio was reported to be associated with blood pressure (BP). A Na/K ratio self-monitoring device using spot urine was established recently. Here, we assessed whether the urinary Na/K ratio change measured using the Na/K device was associated with BP change in a health checkup setting. We targeted 12,890 participants who attended the health checkup in Tome City, Miyagi between 2017 and 2018. Tome City introduced urinary Na/K ratio measurements during health checkups since 2017. For each year, we compared the baseline characteristics according to the urinary Na/K ratio and BP level. We assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, and change in body mass index (BMI) and alcohol intake. The average urinary Na/K ratio was significantly lower in 2018 than in 2017 (5.4 ± 3.0 to 4.9 ± 2.2, P < 0.01). The systolic BP of the participants in 2018 (130.9 ± 17.4 mmHg) was lower than that in 2017 (132.1 ± 17.9 mmHg). Moreover, the change in systolic BP and diastolic BP was positively associated with the change in urinary Na/K ratio. In conclusion, the association of the change in urinary Na/K ratio with hypertension and changes in systolic and diastolic BP can be explained by a change in alcohol intake, BMI, and urinary Na/K ratio. Therefore, measuring the urinary Na/K ratio in community settings is a potential population approach for counteracting hypertension.


Recently, it absolutely was reported that brand new sodium (Na)/potassium (K) ratio is associated with blood pressure levels (BP) within the a corner-sectional study [step 1,2,step three,4]. This is asked since high Na and K intake is actually known getting pertaining to high and you may reduced BP, correspondingly [5,six,7]. At the same time, studies have already been held into site beliefs and you will circumstances adding to new Na/K proportion prior to now year [8, 9].

Sodium/potassium ratio change are from the hypertension changes: chances of society approach for salt/potassium ratio loss in wellness checkup

Within the a community form, it is hard for all of us to evaluate the genuine Na intake while the Na consumption is traditionally assessed of the twenty-four-h urine range. Even when several equations to own estimating Na consumption otherwise K intake using everyday destination urine were has just dependent, this type of equations are not direct enough to give opinions into anyone [10,11,12]. Also, while the equation demands calculating Na, K, and you will creatinine levels from inside the a lab, it will take several weeks to discover the outcomes for anybody. Even though people are aware that sodium prevention is made for decreasing BP, he has got not a chance regarding evaluating the Na level.

Recently, good Na/K ratio mind-keeping track of tool having fun with room urine try created . Though it don't gauge the real Na consumption top, it does give views regarding your urinary Na/K balance within a few minutes. Moreover, an interventional or observational studies with this particular screen suggested that will be a good unit so you can guess new urinary Na/K proportion [13, 14].

Hence, while we don't have any way to gauge the Na/K ratio during the wellness checkup options, we considered that assessing the latest urinary Na/K ratio in a medical checkup site may have the potential to add feedback toward standard society about their Na/K ratio and may even have an impact on impression transform, improvement in step, Na/K ratio cures, and BP prevention. In this investigation, we assessed if the urinary Na/K proportion alter counted on the Na/K ratio measurement product was regarding the BP change independent away from confounding points like bmi (BMI) transform and alter within the alcoholic drinks intake and you will opposed this new BP level and urinary Na/K proportion at area peak.